Reproducible case studies

From graph candidates to validated RNA motifs

These examples show what users can retrieve with RNAdex and where atomic-coordinate validation is still required. Candidate counts are always kept separate from confirmed representatives.

Three motif workflows

Internal loop

Kink-turn

Tandem non-WC G.A topology proposes candidates; stored geometry confirms selected kink-turns.

4 confirmed representatives
View workflow
Internal-loop graph

Sarcin-ricin motif

A formal seven-nucleotide interaction graph projected into RNAdex, then validated from atomic coordinates with official FR3D interaction and geometric criteria.

3 FR3D-validated representatives
View workflow
Four-nucleotide hairpin

GNRA tetraloop

A four-nucleotide hairpin sequence search followed by graph and official FR3D interaction and geometric validation.

3 FR3D-validated representatives
View workflow

How to read these examples

Candidate retrieval

RNAdex stores nucleotide graphs with backbone, Watson-Crick, and generic non-Watson-Crick edges. These features efficiently narrow the structural search space.

Coordinate validation

A generic graph edge does not preserve every interaction family or geometric detail. Each named-motif page therefore states its separate acceptance rule and validation evidence.